Select Publications

  • Pitter F Huesgen, Philipp F Lange , Lindsay D Rogers, Nestor Solis, Ulrich Eckhard, Oded Kleifeld, Theodoros Goulas, F Xavier Gomis-Rüth & Christopher M Overall (2014). LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification Nature Methods 12, 55–58 (2015)
  • Nikolaus Fortelny, Jennifer Cox, Reinhild Kappfelhoff, Amanda E. Starr, Philipp F. Lange, Paul Pavlidis, Christopher M. Overall (2014). Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web PLoS Biology, 12(5):e1001869. PMID: 24865846.
  • Philipp F Lange*, Pitter F Huesgen*, Karen Nguyen, Christopher M Overall (2014) Annotating N termini for the Human Proteome Project: N termini differentiate stable processed protein species from degradation remnants in the human erythrocyte proteome. Journal of Proteome Research13 (4), 2028-2044 (* joint first authors)
  • Huesgen PF*, Lange PF*, Overall CM (2014) Ensembles of protein termini are sensitive and specific proteolytic signature biomarkers of disease, Proteomics – Clinical Applications (* joint first authors)
  • Lange PF, Overall CM (2013) Protein TAILS: When termini tell tales of proteolysis and function. Current Opinion in Chemical Biology 17(1):73-82
  • Philipp F. Lange, Pitter F. Huesgen, Christopher M. Overall (2012). TopFIND 2.0—linking protein termini with proteolytic processing and modifications altering protein functionNucleic acids research. 40(D1): D351-D361.
  • Philipp F. Lange & Christopher M. Overall (2011). TopFIND, a knowledgebase linking protein termini with functionNature Methods 8: 703–704.
  • auf dem Keller U, Bellac CL, Li Y, Lou Y, Lange PF, Ting R, Harwig C, Kappelhoff R, Dedhar S, Adam MJ, Ruth TJ, Bénard F, Perrin DM, Overall CM (2010). Novel matrix metalloproteinase inhibitor [18F]marimastat-­‐aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancerCancer Research 1;70(19):7562-­9.
  • Philipp F. Lange, Lena Wartosch, Thomas J. Jentsch, Jens C. Fuhrmann (2006). ClC–7 requires Ostm1 as a β–subunit to support bone resorption and lysosomal functionNature 440: 220–223.