Infrastructure

Instrumentation Suite

We maintain a state-of-the-art platform of instrumentation and a high-performance computational core to power our analysis.

Our infrastructure is designed for versatility and depth. From routine high-throughput analysis to specialized deep proteome coverage, our instrument ecosystem supports the full spectrum of precision oncology research.

Mass Spectrometry Platform

The Workhorse

Q Exactive HF

The lab’s reliable, high-sensitivity system for routine analysis and first-line method development.

System Specifications

  • Primary Role
    Routine Analysis
  • Paired LC
    nEasy / Evosep
  • Capability
    Established Nanoflow
  • Controller
    Xcalibur (C-1)

The Specialist

timsTOF Ultra

Specialized 4D-proteomics instrument utilizing PASEF. Ideal for sample-limited situations.

System Specifications

  • Primary Role
    Low-Input / High-Sens
  • Paired LC
    Nanoelute 2 / Evosep
  • Capability
    4D-Proteomics (PASEF)
  • Co-Pilot
    Real-time Search Server

The Vanguard

Orbitrap Astral

Next-generation system designed for high-throughput and fast acquisition speeds.

System Specifications

  • Primary Role
    High-Throughput
  • Paired LC
    Vanquish Neo (Future)
  • Capability
    Deep Proteome Coverage
  • Network
    10 Gbps Backbone

Computational Backbone


LANGE-LAB-CORE
Processing Node (E-1)
// The Engine
AMD Threadripper
MaxQuant/DIA-NN

Primary Storage (D-1)
// The Treasury & Dev Hub
Active Data
GPU Accelerated

Live Search Server (C-3)
// The Co-Pilot
Bruker ProteoScape
Real-Time

Legacy Archive (D-2)
// The Vault (Phasing Out)
32 TB Capacity
Historical Data