Select Publications

Comprehensive list at Google Scholar and ORCIDORCID iD icon
Members of the Lange Lab in underlined.

  • Yu H, Xing S, Nierves L, Lange PF, Huan T (2020). Implementing quality control-based signal calibration in mass spectrometry-based metabolomics to overcome the error of fold change calculation caused by nonlinear ESI responses. Analytical Chemistry
  • Richmond AP, Kloet F, Vaz FM, Kampen AHC, Uzozie A, Lange PF, Lin D, Kobor M, Graham E, Mostafavi S, Moreland P, Wasswerman W, Karnebeek C, Kemp S, Engelen M, Multi-omic approach to identify phenotypic modifiers underlying cerebral demyelination in X-linked adrenoleukodystrophy Frontiers in Cell and Developmental Biology
  • Anuli UzozieEnes K. Ergin, Nina Rolf, Janice Tsui, Amanda Lorentzian, Samuel S. Weng, Lorenz Nierves, Theodore G. Smith, C. James Lim, Christopher A. Maxwell, Gregor S.D. Reid, Philipp F. LangePDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways (2019) bioRxiv
  • Samuel SH Weng, Fatih Demir, Enes K. Ergin, Sabrina Dirnberger, Anuli Uzozie, Domenic Tuscher, Lorenz Nierves, Janice Tsui, Pitter F. Huesgen and Philipp F. Lange, Sensitive determination of proteolytic proteoforms in limited microscale proteome samples (2019) Molecular & Cellular Proteomics mcp.TIR119.001560
  • A Lorentzian, A Uzozie, PF Lange, Origins and clinical relevance of proteoforms in pediatric malignancies (2019) Expert review of proteomics 16 (3), 185-200
  • A Lorentzian, JA Biegel, DG Ostrow, SR Rassekh, RJ Deyell, T Triche, K Schultz, J Rozmus, GSD Reid, CJ Lim, PF Lange#, CA Maxwell#. (2018) Tumor variant identification that accounts for the unique molecular landscape of pediatric malignancies. J National Cancer Institute (JNCI) – Cancer Spectrum, 2 (4), pky079 (# joint corresponding author)
  • Connell M, Chen H, Jiang J, Kuan C-W, Fotovati A, Chu T, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel M, Pilarski LM, Simpson EM, Lange PF, Allan DW, Maxwell CA. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. eLIFE. 2017 Oct 10;6. pii: e28672.
  • Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM. TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors. Cell Reports. 2016 Aug 9;16(6):1762-73.
  • Fotelny N, Yang S, Pavlidis P, Lange PF#, Overall CM#. Proteome TopFIND3.0 with TopFINDer and PathFINDer: database analysis tools for the association of protein termini to pre- and post-translational events. Nucleic Acids Research. 2015 Jan;43(Database issue):D290-7. (# joint corresponding author)
  • Pitter F Huesgen, Philipp F Lange , Lindsay D Rogers, Nestor Solis, Ulrich Eckhard, Oded Kleifeld, Theodoros Goulas, F Xavier Gomis-Rüth & Christopher M Overall (2014). LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification Nature Methods 12, 55–58 (2015)
  • Nikolaus Fortelny, Jennifer Cox, Reinhild Kappfelhoff, Amanda E. Starr, Philipp F. Lange, Paul Pavlidis, Christopher M. Overall (2014). Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web PLoS Biology, 12(5):e1001869. PMID: 24865846.
  • Philipp F Lange*, Pitter F Huesgen*, Karen Nguyen, Christopher M Overall (2014) Annotating N termini for the Human Proteome Project: N termini differentiate stable processed protein species from degradation remnants in the human erythrocyte proteome. Journal of Proteome Research13 (4), 2028-2044 (* joint first authors)
  • Huesgen PF*, Lange PF*, Overall CM (2014) Ensembles of protein termini are sensitive and specific proteolytic signature biomarkers of disease, Proteomics – Clinical Applications (* joint first authors)
  • Lange PF, Overall CM (2013) Protein TAILS: When termini tell tales of proteolysis and function. Current Opinion in Chemical Biology 17(1):73-82
  • Philipp F. Lange, Pitter F. Huesgen, Christopher M. Overall (2012). TopFIND 2.0—linking protein termini with proteolytic processing and modifications altering protein functionNucleic Acids Research. 40(D1): D351-D361.
  • Philipp F. Lange & Christopher M. Overall (2011). TopFIND, a knowledgebase linking protein termini with functionNature Methods 8: 703–704.
  • auf dem Keller U, Bellac CL, Li Y, Lou Y, Lange PF, Ting R, Harwig C, Kappelhoff R, Dedhar S, Adam MJ, Ruth TJ, Bénard F, Perrin DM, Overall CM (2010). Novel matrix metalloproteinase inhibitor [18F]marimastat-­‐aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancerCancer Research 1;70(19):7562-­9.
  • Philipp F. Lange, Lena Wartosch, Thomas J. Jentsch, Jens C. Fuhrmann (2006). ClC–7 requires Ostm1 as a β–subunit to support bone resorption and lysosomal functionNature 440: 220–223.